Spinal cord compression due to extramedullary haemopoiesis in myelofibrosis.

نویسندگان

  • G Cook
  • R A Sharp
چکیده

Extramedullary haemopoiesis resulting in spinal cord compression is rare. This report of extramedullary myeloid metaplasia in a patient with myelofibrosis serves to illustrate the value of magnetic resonance imaging (MRI) in the diagnosis and management of good neurological recovery.

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References APPLEBY, A., BATSON, G.A., LASSMAN, L.P. & SIMPSON, C.A. (1964) Spinal cord compression by extramedullary haematopoiesis in myelosclerosis. J. Neurol. Neurosurg. Psychiat. 27, 313. ASK-UPMARK, E. (1945) Tumour-simulating intra-thoracic heterotopia of bone marrow, Acta radiol. (Stockh.), 26, 425. BRANNAN, D. (1927) Extramedullary hematopoiesis in anaemias. Bull. Johns Hopk. Hosp. 41 1...

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Extramedullary haemopoiesis in thalassemia intermedia presenting as paraplegia.

Extramedullary haemopoiesis causing spinal cord compression is a rare manifestation of thalassemia. We describe a 17 year old male with thalassemia intermedia who presented with progressive paraplegia and sphincter disturbance. Magnetic resonance imaging revealed an epidural lesion extending from T5 to T8 compressing the spinal cord. The patient recovered completely after surgical decompression...

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Spinal cord compression by extramedullary haematopoiesis in myelofibrosis.

A 50-year-old man with a 20-year history of myelofibrosis developed mild impairment of dorsal column sensation and ataxia of gait. A myelogram and subsequent peroperative biopsy demonstrated spinal cord compression due to extramedullary haematopoiesis. There was an excellent clinical response to surgery and radiotherapy. The characteristic clinical features and the pathogenesis of this unusual ...

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Spinal cord compression in thalassaemia.

Two cases of spinal cord compression resulting from extramedullary haemopoiesis in patients with thalassaemia of intermediate clinical severity are reported. The association between mild thalassaemia with long survival and the risk of spinal cord compression from extramedullary haemopoietic deposits is emphasised.

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Myelofibrosis presenting as spinal cord compression.

This report describes a case of myelofibrosis presenting as spinal cord compression on account of extramedullary haemopoietic tissue encroaching upon the spinal cord from a large pelvic mass.

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عنوان ژورنال:
  • Journal of clinical pathology

دوره 47 5  شماره 

صفحات  -

تاریخ انتشار 1994